PDB (2008)

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Other Years: 2008 (1, 2) | 2007 | 2006 | 2005 | 2004 | 2003


Contents

+3FCK+

3FCK -231
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3FCK -231
Complex of UNG2 and a fragment-based design inhibitor
Bianchet, M.A., Chung, S., Parker, J.B., Amzel, L.M., Stivers, J.T.
Impact of linker strain and flexibility in the design of a fragment-based inhibitor
Nat.Chem.Biol. 5: 407-413, 2009

PDB Code: 3FCK
PDB Deposition Date: 2008-11-21

+3F80+

3F80 -UNKNOWN-188???
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3F80 -UNKNOWN-188???
(S)-2-amino-6-nitrohexanoic acid binds to human arginase I through multiple nitro-metal coordination interactions in the binuclear manganese cluster. Resolution 1.60 A.
Di Costanzo, L., Christianson, D.W.
(S)-2-amino-6-nitrohexanoic acid binds to human arginase I through multiple nitro-metal coordination interactions in the binuclear manganese cluster
J.Am.Chem.Soc. 130: 17254-17255, 2008

PDB Code: 3F80
PDB Deposition Date: 2008-11-10

=3F55= (On Hold)

Image:3F55.jpg

Crystal structure of the native endo beta-1,3-glucanase (Hev b 2), A major allergen from hevea brasiliensis (space group P41)
Fuentes-Silva, D., Munoz-Cruz, S., Mendoza-Hernandez, G., Palomares, L.A., Yepez-Mulia, L., Rodriguez-Romero, A.


PDB Code: 3F55
PDB Deposition Date: 2008-11-03

+3F39+

3F39 -97
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3F39 -97
Apoferritin: complex with phenol
Vedula, L.S., Economou, N.J., Rossi, M.J., Eckenhoff, R.G., Loll, P.J.
A unitary anesthetic-binding site at high resolution.
J.Biol.Chem. , 2009

PDB Code: 3F39
PDB Deposition Date: 2008-10-30

+3F38+

3F38 -97
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3F38 -97
Apoferritin: complex with 2,6-dimethylphenol
Vedula, L.S., Economou, N.J., Rossi, M.J., Eckenhoff, R.G., Loll, P.J.
A unitary anesthetic-binding site at high resolution.
J.Biol.Chem. , 2009

PDB Code: 3F38
PDB Deposition Date: 2008-10-30

+3F37+

3F37 -97
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3F37 -97
Apoferritin: complex with 2,6-dimethylphenol
Vedula, L.S., Economou, N.J., Rossi, M.J., Eckenhoff, R.G., Loll, P.J.
A unitary anesthetic-binding site at high resolution.
J.Biol.Chem. , 2009

PDB Code: 3F37
PDB Deposition Date: 2008-10-30

+3F36+

3F36 -97
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3F36 -97
Apoferritin: complex with 2-isopropylphenol
Vedula, L.S., Economou, N.J., Rossi, M.J., Eckenhoff, R.G., Loll, P.J.
A unitary anesthetic-binding site at high resolution.
J.Biol.Chem. , 2009

PDB Code: 3F36
PDB Deposition Date: 2008-10-30

+3F35+

3F35 -97
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3F35 -97
Apoferritin: complex with 2,6-diethylphenol
Vedula, L.S., Economou, N.J., Rossi, M.J., Eckenhoff, R.G., Loll, P.J.
A unitary anesthetic-binding site at high resolution.
J.Biol.Chem. , 2009

PDB Code: 3F35
PDB Deposition Date: 2008-10-30

+3F34+

3F34 -97
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3F34 -97
Apoferritin: complex with 2,6-diethylphenol
Vedula, L.S., Economou, N.J., Rossi, M.J., Eckenhoff, R.G., Loll, P.J.
A unitary anesthetic-binding site at high resolution.
J.Biol.Chem , 2009

PDB Code: 3F34
PDB Deposition Date: 2008-10-30

+3F33+

3F33 -97
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3F33 -97
Apoferritin: complex with propofol
Vedula, L.S., Economou, N.J., Rossi, M.J., Eckenhoff, R.G., Loll, P.J.
A unitary anesthetic-binding site at high resolution.
J.Biol.Chem. , 2009

PDB Code: 3F33
PDB Deposition Date: 2008-10-30

+3F32+

3F32 -97
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3F32 -97
Horse spleen apoferritin
Vedula, L.S., Economou, N.J., Rossi, M.J., Eckenhoff, R.G., Loll, P.J.
A unitary anesthetic-binding site at high resolution.
J.Biol.Chem. , 2009

PDB Code: 3F32
PDB Deposition Date: 2008-10-30

=3F1V= (On Hold)

Image:3F1V.jpg

E. coli Beta Sliding Clamp, 148-153 Ala Mutant
Cody, V.


PDB Code: 3F1V
PDB Deposition Date: 2008-10-28

=3EWE=

3EWE -236
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3EWE -236
Crystal Structure of the Nup85/Seh1 Complex
Brohawn, S.G., Leksa, N.C., Rajashankar, K.R., Schwartz, T.U.
Structural evidence for common ancestry of the nuclear pore complex and vesicle coats.
Science 322: 1369-1373, 2008

PDB Code: 3EWE
PDB Deposition Date: 2008-10-14

+3ETP+

3ETP -153_SKIa
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3ETP -153_SKIa
The crystal structure of the ligand-binding domain of the EphB2 receptor at 2.0 A resolution
Goldgur, Y., Paavilainen, S., Nikolov, D.B, Himanen, J.P.
The crystal structure of the ligand-binding domain of the EphB2 receptor at 2.0 A resolution
TO BE PUBLISHED

PDB Code: 3ETP
PDB Deposition Date: 2008-10-08

=3EM5= (On Hold)

Image:3EM5.jpg

Crystal structure of a native endo beta-1,3-glucanase (Hev b 2), a major allergen from Hevea brasiliensis
Fuentes-Silva, D., Munoz-Cruz, S., Yepez-Mulia, L., Mendoza-Hernandez, G., Palomares, L.A., Rodriguez-Romero, A.


PDB Code: 3EM5
PDB Deposition Date: 2008-09-23

+3EJ6+

3EJ6 -34b
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3EJ6 -34b
Neurospora Crassa Catalase-3 Crystal Structure
Diaz, A., Valdes, V.-J., Rudino-Pinera, E., Horjales, E., Hansberg, W.
Structure-Function Relationships in Fungal Large-Subunit Catalases
J.Mol.Biol. 386: 218-232,2009


PDB Code: 3EJ6
PDB Deposition Date: 2008-09-17

+3EG6+

3EG6 -UNKNOWN
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3EG6 -UNKNOWN
Structure of WDR5 bound to MLL1 peptide
Patel, A., Dharmarajan, V., Cosgrove, M.S.
Structure of WDR5 bound to Mixed Lineage Leukmemia protein-1 peptide
TO BE PUBLISHED


PDB Code: 3EG6
PDB Deposition Date: 2008-09-10

+3EGH+ (On Hold)

Image:3EGH.jpg

Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1), the PP1 binding and PDZ domains of Spinophilin and the small natural molecular toxin Nodularin-R
Ragusa, M.J., Page, R., Peti, W.


PDB Code: 3EGH
PDB Deposition Date: 2008-09-10

+3EGG+ (On Hold)

Image:3EGG.jpg

Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1) and the PP1 binding and PDZ domains of Spinophilin
Ragusa, M.J., Page, R., Peti, W.


PDB Code: 3EGG
PDB Deposition Date: 2008-09-10

+3E7B+

3E7B -227
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3E7B -227
Crystal Structure of Protein Phosphatase-1 Bound to the natural toxin inhibitor Tautomycin
Kelker, M.S., Page, R., Peti, W.
Crystal Structures of Protein Phosphatase-1 Bound to Nodularin-R and Tautomycin: Novel Scaffolds for Structure Based Drug Design of Serine/Threonine Phosphatase Inhibitors
TO BE PUBLISHED

PDB Code: 3E7B
PDB Deposition Date: 2008-08-18

+3E7A+

3E7A -227
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3E7A -227
Crystal Structure of Protein Phosphatase-1 Bound to the natural toxin Nodularin-R
Kelker, M.S., Page, R., Peti, W.
Crystal Structures of Protein Phosphatase-1 Bound to Nodularin-R and Tautomycin: Novel Scaffolds for Structure Based Drug Design of Serine/Threonine Phosphatase Inhibitors
TO BE PUBLISHED

PDB Code: 3E7A
PDB Deposition Date: 2008-08-18

=3DWN=

3DWN -47b
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3DWN -47b
Crystal structure of the long-chain fatty acid transporter FadL mutant A77E/S100R
Hearn, E.M., Patel, D.R., Lepore, B.W., Indic, M., van den Berg, B.
Transmembrane passage of hydrophobic compounds through a protein channel wall.
Nature 458: 367-370, 2009

PDB Code: 3DWN
PDB Deposition Date: 2008-07-22

=3DWO=

3DWO -47b
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3DWO -47b
Crystal structure of a Pseudomonas aeruginosa FadL homologue
Hearn, E.M., Patel, D.R., Lepore, B.W., Indic, M., van den Berg, B
Membrane transport of hydrophobic compounds by lateral diffusion
To be Published

PDB Code: 3DWO
PDB Deposition Date: 2008-07-22

+3DWH+

3DWH -UNKNOWN
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3DWH -UNKNOWN
Structural and Functional Analysis of SRA domain
Qian, C., Jakoncic, J., Zhou, M.
Structure and hemimethylated CpG binding of the SRA domain from human UHRF1
TO BE PUBLISHED

PDB Code: 3DWH
PDB Deposition Date: 2008-07-22

+3DU6+

3DU6 -180
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3DU6 -180
Structure of the catalytic subunit of telomerase, TERT
Skordalakes, E.
Structure of the Tribolium castaneum telomerase catalytic subunit TERT.
Nature 455: 633-637, 2008

PDB Code: 3DU6
PDB Deposition Date: 2008-07-16

+3DU5+

3DU5 -180
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3DU5 -180
Structure of the catalytic subunit of telomerase, TERT
Skordalakes, E.
Structure of the Tribolium castaneum telomerase catalytic subunit TERT.
Nature 455: 633-637, 2008

PDB Code: 3DU5
PDB Deposition Date: 2008-07-16

+3DM7+

3DM7 -UNKNOWN
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3DM7 -UNKNOWN
Crystal Structure of the Vps75 Histone Chaperone
Tang, Y., Marmorstein, R.
Structure of Vps75 and implications for histone chaperone function.
Proc.Natl.Acad.Sci.Usa 105: 12206-12211, 2008

PDB Code: 3DM7
PDB Deposition Date: 2008-06-30

=3DJ8=

3DJ8 -188
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3DJ8 -188
Synthesis of (S)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase I
Di Costanzo, L., Christianson, D.W.
Synthesis of (2S)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase I
Org.Biomol.Chem. 6: 3240-3243, 2008

PDB Code: 3DJ8
PDB Deposition Date: 2008-06-22

+3DCB+

3DCB -250
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3DCB -250
Crystal structure of the Drosophila kinesin family member NOD in complex with AMPPNP
Cochran, J.C., Mulko, N.K., Kull, F.J.
ATPase cycle of the nonmotile kinesin NOD allows microtubule end tracking and drives chromosome movement. Cell(Cambridge,Mass.) 136: 110-122
Cell(Cambridge,Mass.) 136: 110-122, 2009

PDB Code: 3DCB
PDB Deposition Date: 2008-06-03

+3DC4+

3DC4 -250
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3DC4 -250
Crystal structure of the Drosophila kinesin family member NOD in complex with ADP
Cochran, J.C., Mulko, N.K., Kull, F.J.
ATPase cycle of the nonmotile kinesin NOD allows microtubule end tracking and drives chromosome movement. Cell(Cambridge,Mass.) 136: 110-122
Cell(Cambridge,Mass.) 136: 110-122, 2009

PDB Code: 3DC4
PDB Deposition Date: 2008-06-03

+3D62+

3D62 -204
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3D62 -204
Development of Broad-Spectrum Halomethyl Ketone Inhibitors Against Coronavirus Main Protease 3CLpro
Bacha, U., Barrila, J., Gabelli, S.B., Kiso, Y., Amzel, L.M., Freire, E.
Development of Broad-Spectrum Halomethyl Ketone Inhibitors Against Coronavirus Main Protease 3CLpro
CHEM.BIOL.DRUG.DES. 72:34-49, 2008

PDB Code: 3D62
PDB Deposition Date: 2008-05-18

+3D44+

3D44 -150
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3D44 -150
Crystal structure of HePTP in complex with a dually phosphorylated Erk2 peptide mimetic
Critton, D.A., Tortajada, A., Stetson, G., Page, R.
Structural basis of substrate recognition by hematopoietic tyrosine phosphatase.
Biochemistry 47: 13336-13345, 2009

PDB Code: 3D44
PDB Deposition Date: 2008-05-13

+3D42+

3D42 -150
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3D42 -150
Crystal structure of HePTP in complex with a monophosphorylated Erk2 peptide
Critton, D.A., Tortajada, A., Stetson, G., Page, R.
Structural basis of substrate recognition by hematopoietic tyrosine phosphatase.
Biochemistry 47: 13336-13345, 2008

PDB Code: 3D42
PDB Deposition Date: 2008-05-13

=3D36=

3D36 -153_RUa
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3D36 -153_RUa
How to Switch Off a Histidine Kinase: Crystal Structure of Geobacillus stearothermophilus KinB with the Inhibitor Sda
Bick, M.J., Lamour, V., Rajashankar, K.R., Gordiyenko, Y., Robinson, C.V., Darst, S.A.
How to Switch Off a Histidine Kinase: Crystal Structure of Geobacillus stearothermophilus KinB with the inhibitor Sda.
J.Mol.Biol.

PDB Code: 3D36
PDB Deposition Date: 2008-05-09

+3D35+

3D35 -203
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3D35 -203
Crystal Structure of RTT109-AC-COA Complex
Tang, Y., Marmorstein, R.
Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP.
Nat.Struct.Mol.Biol. 15: 738-745, 2008

PDB Code: 3D35
PDB Deposition Date: 2008-05-09

+3CST+

3CST -263
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3CST -263
Crystal structure of PI3K p110gamma catalytical domain in complex with organoruthenium inhibitor E5E2
Xie, P., Marmorstein, R.
Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity.
Acs Chem.Biol. 3: 305-316, 2008

PDB Code: 3CST
PDB Deposition Date: 2008-04-10

=3CSF=

3CSF -263
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3CSF -263
Crystal structure of PI3K p110gamma catalytical domain in complex with organoruthenium inhibitor DW2
Xie, P., Marmorstein, R.
Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity.
Acs Chem.Biol. 3: 305-316, 2008

PDB Code: 3CSF
PDB Deposition Date: 2008-04-09

+3COA+

3COA -211
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3COA -211
Crystal Structure of FoxO1 DBD Bound to IRE DNA
Brent, M.M., Anand, R., Marmorstein, R.
Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification.
Structure 16: 1407-1416, 2008

PDB Code: 3COA
PDB Deposition Date: 2008-03-27

=3CO7=

3CO7 -211
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3CO7 -211
Crystal Structure of FoxO1 DBD Bound to DBE2 DNA
Brent, M.M., Anand, R., Marmorstein, R.
Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification.
Structure 16: 1407-1416, 2008

PDB Code: 3CO7
PDB Deposition Date: 2008-03-27

+3CO6+

3CO6 -211
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3CO6 -211
Crystal Structure of FoxO1 DBD Bound to DBE1 DNA
Brent, M.M., Anand, R., Marmorstein, R.
Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification.
Structure 16: 1407-1416, 2008

PDB Code: 3CO6
PDB Deposition Date: 2008-03-27

+3CMG+

3CMG -UNKNOWN
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3CMG -UNKNOWN
Crystal structure of putative beta-galactosidase from Bacteroides fragilis
Ramagopal, U.A., Rutter, M., Toro, R., Hu, S., Maletic, M., Gheyi, T., Sauder, J.M., Burley, S.K., Almo, S.C., New York Structural GenomiX Research Consortium (NYSGXRC)
Crystal structure of putative beta-galactosidase from Bacteroides fragilis.
TO BE PUBLISHED

PDB Code: 3CMG
PDB Deposition Date: 2008-03-21

+3CMF+

3CMF -229
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3CMF -229
Crystal structure of human liver 5beta-reductase (AKR1D1) in complex with NADP and CORTISONE. Resolution 1.90 A.
Di Costanzo, L., Drury, J., Penning, T.M., Christianson, D.W.
Crystal Structure of Human Liver {Delta}4-3-Ketosteroid 5{beta}-Reductase (AKR1D1) and Implications for Substrate Binding and Catalysis.
J.Biol.Chem. 283:16830-16839, 2008

PDB Code: 3CMF
PDB Deposition Date: 2008-03-21

=3CAK=

3CAK -153_AECOMd
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3CAK -153_AECOMd
X-ray structure of WT PTE with ethyl phosphate
Kim, J., Tsai, P.-C., Almo, S.C., Raushel, F.M.
Structure of diethyl phosphate bound to the binuclear metal center of phosphotriesterase.
Biochemistry 47: 9497-9504


PDB Code: 3CAK
PDB Deposition Date: 2008-02-20

=3C9J=

3C9J -169
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3C9J -169
The Crystal structure of Transmembrane domain of M2 protein and Amantadine complex
Stouffer, A.L., Acharya, R., Salom, D.
Structural basis for the function and inhibition of an influenza virus proton channel
Nature 451: 596-600, 2008


PDB Code: 3C9J
PDB Deposition Date: 2008-02-15