Publications-2011

From X6AWiki

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--- Year 2011 ---

  • Cochran JC, Zhao YC, Wilcox DE, Kull FJ.(2011) x6a250

A metal switch for controlling the activity of molecular motor proteins.
Nat Struct Mol Biol. 19(1):122-7..


  • Lott K, Bhardwaj A, Sims PJ, Cingolani G.(2011) x6a65

A minimal nuclear localization signal (NLS) in human phospholipid scramblase 4 that binds only the minor NLS-binding site of importin alpha1.
J Biol Chem. 286(32):28160-9..


  • Garnham, C.P., Campbell, R.L., Davies, P.L.(2011) x6a282

Anchored clathrate waters bind antifreeze proteins to ice.
Proc.Natl.Acad.Sci.USA 108: 7363-7367.


  • Ilies M, Di Costanzo L, Dowling DP, Thorn KJ, Christianson DW.(2011) x6a188

Binding of α,α-disubstituted amino acids to arginase suggests new avenues for inhibitor design.
J Med Chem. 54(15):5432-43.


  • Sainlos, M., Tigaret, C., Poujol, C., Olivier, N.B., Bard, L., Breillat, C., Thiolon, K., Choquet, D., Imperiali, B.(2011) x6a173

Biomimetic divalent ligands for the acute disruption of synaptic AMPAR stabilization.
Nat.Chem.Biol. 7: 81-91.


  • Yuan, J., Simpson, R.D., Zhao, W., Tice, C.M., Xu, Z., Cacatian, S., Jia, L., Flaherty, P.T., Guo, J., Ishchenko, A., Wu, Z., McKeever, B.M., Scott, B.B., Bukhtiyarov, Y., Berbaum, J., Panemangalore, R., Bentley, R., Doe, C.P., Harrison, R.K., McGeehan, G.M., Singh, S.B., Dillard, L.W., Baldwin, J.J., Claremon, D.A.(2011) x6a134

Biphenyl/diphenyl ether renin inhibitors: Filling the S1 pocket of renin via the S3 pocket.
Bioorg.Med.Chem.Lett. 21: 4836-4843.


  • Gabelli SB, Duong-Ly K, Brower ET, Amzel LM.(2011) x6a195

Capitalizing on tumor genotyping: Towards the design of mutation specific inhibitors of phosphoinsitide-3-kinase.
Adv Enzyme Regul. 51(1):273-9..


  • Amacher JF, Cushing PR, Weiner JA, Madden DR.(2011) x6a300

Crystallization and preliminary diffraction analysis of the CAL PDZ domain in complex with a selective peptide inhibitor.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 67(Pt 5):600-3..


  • Roy A, Bhardwaj A, Cingolani G.(2011) MOR171

Crystallization of the nonameric small terminase subunit of bacteriophage P22.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 67(Pt 1):104-10.


  • Weeks SD, Grasty KC, Hernandez-Cuebas L, Loll PJ.(2011) x6a299

Crystal structure of a Josephin-ubiquitin complex: evolutionary restraints on ATAXIN-3 deubiquitinating activity.
J Biol Chem. 286: 4555-4565.


  • Hernández-Santoyo A, Landa A, González-Mondragón E, Pedraza-Escalona M, Parra-Unda R, Rodríguez-Romero A.(2011) x6a191

Crystal structure of Cu / Zn superoxide dismutase from Taenia solium reveals metal-mediated self-assembly.
FEBS J. 278(18):3308-18..


  • Yao G, Zong Y, Gu S, Zhou J, Xu H, Mathews II, Jin R.(2011) x6a255

Crystal structure of the glutamate receptor GluA1 N-terminal domain.
Biochem J. 438(2):255-63..


  • Pan R.; Sampson J.M.; Spurrier B.; Totrov M.; O'Neal T.; Williams C.; Boliar S.; Allen S.; Mulenga J.; Robinson J.; Derdeyn C.A.; Gorny M.K.; Zolla-Pazner S.; Kong X.(2011) x6a330

Crystal structures of human anti-V2 mAbs 697-30D and 8. 9D and what we can learn from their antigen-binding sites [Abstract]
AIDS RESEARCH & HUMAN RETROVIRUSES. 27(10):A120-A121.


  • Jia, L., Simpson, R.D., Yuan, J., Xu, Z., Zhao, W., Cacatian, S., Tice, C.M., Guo, J., Ishchenko, A., Singh, S.B., Wu, Z., McKeever, B.M., Bukhtiyarov, Y., Johnson, J.A., Doe, C.P., Harrison, R.K., McGeehan, G.M., Dillard, L.W., Baldwin, J.J., Claremon, D.A.(2011) x6a134

Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility.
ACS MED.CHEM.LETT. 2: 747-751.


  • Gorny MK, Sampson J, Li H, Jiang X, Totrov M, Wang XH, Williams C, O'Neal T, Volsky B, Li L, Cardozo T, Nyambi P, Zolla-Pazner S, Kong XP.(2011) x6a330

Human anti-V3 HIV-1 monoclonal antibodies encoded by the VH5-51/VL lambda genes define a conserved antigenic structure.
PLoS One. 6(12):e27780..


  • Kocher, O., Birrane, G., Yesilaltay, A., Shechter, S., Pal, R., Daniels, K., Krieger, M.(2011) x6a336

Identification of the PDZ3 Domain of the Adaptor Protein PDZK1 as a Second, Physiologically Functional Binding Site for the C Terminus of the High Density Lipoprotein Receptor Scavenger Receptor Class B Type I.
J.Biol.Chem. 286: 25171-25186.


  • Venticinque L, Jamieson KV, Meruelo D.(2011) x6a193

Interactions between laminin receptor and the cytoskeleton during translation and cell motility.
PLoS One. 6(1):e15895.


  • Schuller AP, Harkisheimer MJ, Skordalakes E.(2011) x6a180

In vitro reconstitution of the active T. castaneum telomerase.
J Vis Exp. (53). pii: 2799..


  • Lepore, B.W., Indic, M., Pham, H., Hearn, E.M., Patel, D.R., van den Berg, B.(2011) x6a47b

Ligand-gated diffusion across the bacterial outer membrane.
Proc.Natl.Acad.Sci.USA 108: 10121-10126.


  • Cheng, W.W., McCoy, J.G., Thompson, A.N., Nichols, C.G., Nimigean, C.M.(2011) x6a304

Mechanism for selectivity-inactivation coupling in KcsA potassium channels.
Proc.Natl.Acad.Sci.USA 108: 5272-5277.


  • Carl L. Hansen, Morten Sommer, Stephen R. Quake(2011) PRO3

Microfluidic protein crystallography
Patent US 7927422.


  • Bonsor, D.A., Postel, S., Pierce, B.G., Wang, N., Zhu, P., Buonpane, R.A., Weng, Z., Kranz, D.M., Sundberg, E.J.(2011) x6a248

Molecular basis of a million-fold affinity maturation process in a protein-protein interaction.
J.Mol.Biol. 411: 321-328.


  • Yuan, H., Rossetto, D., Mellert, H., Dang, W., Srinivasan, M., Johnson, J., Hodawadekar, S., Ding, E.C., Speicher, K., Abshiru, N., Perry, R., Wu, J., Yang, C., Zheng, Y.G., Speicher, D.W., Thibault, P., Verreault, A., Johnson, F.B., Berger, S.L., Sternglanz, R., McMahon, S.B., Cote, J., Marmorstein, R.(2011) x6a311

MYST protein acetyltransferase activity requires active site lysine autoacetylation.
Embo J. 31(1):58-70..


  • Diaz-Sanchez, A.G., Gonzalez-Segura, L., Rudino-Pinera, E., Lira-Rocha, A., Torres-Larios, A., Munoz-Clares, R.A.(2011) x6a66

Novel Nadph-Cysteine Covalent Adduct Found in the Active Site of an Aldehyde Dehydrogenase.
Biochem.J. 439(3):443-52.


  • M Tony Hollingsworth, Gerald W Hart, James C Paulson, Elizabeth Stansell, Kevin Canis, I-Cheuh Huang, Maria Panico, Howard Morris, Stuart Haslam, Michael Farzan, [......], Kazunori Hamamura, Takenosuke Yoshida, Kaoru Akita, Tetsuya Okajima, Keiko Furukawa, Takeshi Urano, Koichi Furukawa, L Renee Ruhaak, Suzanne Miyamoto, Carlito B Lebrilla(2011) x6a283

Program and abstracts for the 2011 Meeting of the Society for Glycobiology.
Glycobiology. 21(11):1454-531.


  • Primo ME, Jakoncic J, Noguera ME, Risso VA, Sosa L, Sica MP, Solimena M, Poskus E, Ermácora MR.(2011) x6a383

Protein-protein interactions in crystals of the human receptor-type protein tyrosine phosphatase ICA512 ectodomain.
PLoS One. 6(9):e24191..


  • Vasquez-Del Carpio R, Silverstein TD, Lone S, Johnson RE, Prakash L, Prakash S, Aggarwal AK.(2011) x6a62

Role of human DNA polymerase κ in extension opposite from a cis-syn thymine dimer.
J Mol Biol. 408(2):252-61..


  • Spurrier, B., Sampson, J.M., Totrov, M., Li, H., O'Neal, T., Williams, C., Robinson, J., Gorny, M.K., Zolla-Pazner, S., Kong, X.P.(2011) x6a330

Structural analysis of human and macaque mAbs 2909 and 2.5B: implications for the configuration of the quaternary neutralizing epitope of HIV-1 gp120.
Structure 19: 691-699.


  • Nguyen TT, Chang SC, Evnouchidou I, York IA, Zikos C, Rock KL, Goldberg AL, Stratikos E, Stern LJ.(2011) x6a241

Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1.
Nat Struct Mol Biol. 18(5):604-13..


  • Butler EB, Xiong Y, Wang J, Strobel SA.(2011) x6a242

Structural basis of cooperative ligand binding by the glycine riboswitch.
Chem Biol. 18(3):293-8..


  • Jamieson KV, Hubbard SR, Meruelo D.(2011) x6a193

Structure-guided identification of a laminin binding site on the laminin receptor precursor.
J Mol Biol. 405(1):24-32..


  • Cingolani, G. and Duncan, T.M.(2011) x6a93

Structure of the ATP synthase catalytic complex (F1) from Escherichia coli in an auto-inhibited conformation.
Nat Struct Mol Biol. 18(6):701-7..


  • Brown, B.L., Wood, T.K., Peti, W., Page, R.(2011) x6a226

Structure of the E. coli antitoxin MQSA (YGIT/B3021) bound to its gene promoter reveals extensive domain rearrangements and the specificity of transcriptional regulation.
J Biol Chem. 286: 2285-2296.


  • Menon, S., Wang, S.(2011) x6a94

Structure of the Response Regulator PhoP from Mycobacterium tuberculosis Reveals a Dimer through the Receiver Domain.
Biochemistry 50: 5948-5957.


  • Tang Y, Holbert MA, Delgoshaie N, Wurtele H, Guillemette B, Meeth K, Yuan H, Drogaris P, Lee EH, Durette C, Thibault P, Verreault A, Cole PA, Marmorstein R.(2011) x6a311

Structure of the Rtt109-AcCoA/Vps75 complex and implications for chaperone-mediated histone acetylation.
Structure. 19(2):221-31..


  • San Luis B, Sondgeroth B, Nassar N, Carpino N.(2011) x6a219

Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathways.
J Biol Chem. 286(18):15943-54..


  • Vaidya S, Velázquez-Delgado EM, Abbruzzese G, Hardy JA.(2011) x6a179

Substrate-Induced Conformational Changes Occur in All Cleaved Forms of Caspase-6.
J Mol Biol. 406: 75-91.


  • Mason M, Schuller A, Skordalakes E.(2011) x6a180

Telomerase structure function.
Curr Opin Struct Biol. 21(1):92-100.


  • Tomanicek SJ, Wang KK, Weiss KL, Blakeley MP, Cooper J, Chen Y, Coates L.(2011) x6a312

The active site protonation states of perdeuterated Toho-1 β-lactamase determined by neutron diffraction support a role for Glu166 as the general base in acylation.
FEBS Lett. 585(2):364-8..


  • Yeh, T.L., Lee, C.Y., Amzel, L.M., Espenshade, P.J., Bianchet, M.A.(2011) x6a244

The hypoxic regulator of sterol synthesis nro1 is a nuclear import adaptor.
Structure 19: 503-514.


  • Guce AI, Clark NE, Rogich JJ, Garman SC.(2011) x6a200

The Molecular Basis of Pharmacological Chaperoning in Human α-Galactosidase.
Chem Biol. 18(12):1521-6..


  • Duong-Ly KC, Gabelli SB, Xu W, Dunn CA, Schoeffield AJ, Bessman MJ, Amzel LM.(2011) x6a183

The Nudix hydrolase CDP-chase, a CDP-choline pyrophosphatase, is an asymmetric dimer with two distinct enzymatic activities.
J Bacteriol. 193(13):3175-85..


  • Serrano-Posada H, Valderrama B, Stojanoff V, Rudiño-Piñera E.(2011) x6a174

Thermostable multicopper oxidase from Thermus thermophilus HB27: crystallization and preliminary X-ray diffraction analysis of apo and holo forms.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 67(Pt 12):1595-8..


  • Olia, A.S, Prevelige Jr., P.E., Johnson, J.E. and Cingolani, G.(2011) x6a155

Three-dimensional structure of a viral genome-delivery portal vertex.
Nat Struct Mol Biol. 18(5):597-603..


  • Dou X, Menkari CE, Shanmugasundararaj S, Miller KW, Charness ME.(2011) x6a74

Two alcohol binding residues interact across a domain interface of the L1 neural cell adhesion molecule and regulate cell adhesion.
J Biol Chem. 286(18):16131-9.


  • Zolla-Pazner S.; Cardozo T.; De Camp A.; Haynes B.; Kim J.; Kong X.; Michael N.; Rerks-Ngarm S.; Williams C.(2011) x6a330

V2-reactive antibodies in RV144 vaccinees' plasma [Abstract]
AIDS RESEARCH & HUMAN RETROVIRUSES. 27(10):A21-A21.


  • Critton DA, Tautz L, Page R.(2011) x6a150

Visualizing Active-Site Dynamics in Single Crystals of HePTP: Opening of the WPD Loop Involves Coordinated Movement of the E Loop.
J Mol Biol. 405(3):619-29.

--- Year 2011 (NO Project) ---

  • Boto AN, Xu W, Jakoncic J, Pannuri A, Romeo T, Bessman MJ, Gabelli SB, Amzel LM.(2011)UNKNOWN

Structural Studies of the Nudix GDP-mannose Hydrolase from E. coli Reveals a New Motif for Mannose Recognition.
Proteins. 79(8):2455–2466.


  • Witkowski WA, Hardy JA.(2011) UNKNOWN

A designed redox-controlled caspase.
Protein Sci. 20(8):1421-31.


  • Bhardwaj, A., Molineux, I.J., Casjens, S.R., Cingolani, G.(2011) UNKNOWN

Atomic structure of bacteriophage Sf6 tail needle knob.
J.Biol.Chem. 286:30867-30877.


  • Kulathila, R., Kulathila, R., Indic, M., van den Berg, B.(2011) UNKNOWN

Crystal structure of Escherichia coli CusC, the outer membrane component of a heavy metal efflux pump.
Plos One 6: e15610-e15610.


  • Li, X., Ji, W., Zhang, R., Folta-Stogniew, E., Min, W., Boggon, T.J.(2011) UNKNOWN

Molecular Recognition of Leucine-Aspartate Repeat (LD) Motifs by the Focal Adhesion Targeting Homology Domain of Cerebral Cavernous Malformation 3 (CCM3).
J.Biol.Chem. 286: 26138-26147.


  • Liszczak, G., Arnesen, T., Marmorstein, R.,(2011) UNKNOWN

Structure of a Ternary Naa50p (NAT5/SAN) N-terminal Acetyltransferase Complex Reveals the Molecular Basis for Substrate-specific Acetylation.
J.Biol.Chem. 286: 37002-37010.


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